Philadelphia plane crash latest: Six people killed in medical plane ...

Videos of the crash show the plane coming down quickly and sparking a huge fireball.

Witnesses described shrapnel damaging cars and sending burning debris into the streets. Photos of the aftermath show burning, mangled cars.

One man who spoke with CBS, the BBC's US partner, said he was driving when he heard a whirring sound and then a loud explosion.

"Everyone just started screaming," he said.

"I saw blinking lights coming from the sky. And I just saw them going down," a 10-year-old boy told CBS on his way home from hockey practice. "It was really scary."

One witness told local media that the explosion "lit up the whole sky".

"I just saw a plane basically hit the building and it exploded. The sky lit up and I pulled over and basically, it was just real bad around here," the witness told WPVI-TV, external, describing the crash as feeling like an earthquake.

Ryan Tian, 23, told The Philadelphia Inquirer, external that he was getting dinner when he saw a "massive fireball" that turned the sky orange.

"I thought we were getting attacked by something," he said.